Understanding molecular mechanisms of cell death
How cells respond to stresses such as infectious microbes or malignant transformations (cancer) is important for host survival. Most times, the cells need to be eliminated to protect the host. Our lab is interested in understanding the mechanism by which cells die in response to different stresses.
Dynamics of cell identity establishment in the embryo
We study the dynamics of fundamental cellular processes in developing cells; and apply single-cell imaging and sequencing approaches to uncover principles that drive cell identity establishment and how these can be dysregulated in disease states.
Using chemistry to better identify and treat cancer
Our organic and chemical biology lab, in close collaboration with clinicians, is on a mission to develop molecules to treat or identify tumors in efforts to improve the lifespan of cancer patients.
Research in health economics and policy
Eric T. Roberts, PhD is an Associate Professor in the Department of General Internal Medicine at the Perelman School of Medicine. He is a health economist who studies the delivery and financing of care in U.S. public insurance programs and health care delivery systems. Dr. Roberts’ research program encompasses three intersecting areas: 1) health insurance for low-income individuals with Medicare and Medicaid (the “dual eligibles”), 2) Medicare and Medicaid managed care, and 3) the effects of payment and delivery system reform on health care disparities. His research uses simulation and econometric techniques for causal inference to inform policymakers and practitioners about the effects of insurance, payment, and delivery system reform policies on the care of vulnerable populations.
Cerebrovascular Neurosurgery Imaging Research
Dr Choudhri is a cerebrovascular and endovascular neurosurgeon who focuses on treatment of blood vessels disorders. His research encompasses novel imaging methods for cerebrovascular conditions such as brain aneurysms, stroke, pulsatile tinnitus.
Respiratory Viruses (Coronaviruses & Influenza)
Zoonotic viral pathogens have caused the largest known epidemics and pandemics throughout human history. My research centers on understanding key virus–host interactions and their impact on viral replication and pathogenesis, and to use these insights to develop novel methodologies to alleviate human disease.
Immunoengineering for Cardiovascular Disease
Cardiovascular disease is the leading cause of death worldwide. There is an urgent clinical need for treatments distinct from current options. To tackle this problem, we leverage the immune system, protein engineering, and pharmacokinetic modeling.
Global health - advancing child health in Consuelo, a rural town in the Dominican Republic
CHOP's Global Health Center and our Dominican partners have developed a program that aims to improve the health of children in the rural town of Consuelo.
Clinical Research in Mitochondrial Disease
Clinical research opportunities available at various times throughout the year focused on the care of children and adults with mitochondrial disease.
Clinical Cardiac Electrophysiology, Pediatric and Adult Congenital Cardiac Electrophysiology
Clinical cardiac electrophysiologist interested in collaborating and provide mentorship to develop predictive tools and tech to solve real world problems in the world of cardiac rhythm disorders and pacing