Mentor Areas
The Burslem lab is interested in developing chemical tools to understand and modulate lysine post-translational modifications, specifically acetylation and ubiquitination. The laboratory is particularly interested in novel pharmacological approaches to modulate post-translational modifications which regulate gene expression and protein stability with a focus on understanding and treating haematological malignancies. We employ a multidisciplinary approach including synthetic chemistry, biochemistry, biophysics and cell biology to probe biological systems in cancer biology.
Description:
The Burslem lab is interested in understanding the roles of lysine post-translational modifications and developing chemical tools to modulate them, with the aim of developing novel therapeutic approaches.
Projects will vary but may include synthetic chemistry, molecular biology, biochemistry and/or cell biology.
Interested students to contact George to discuss possibilities.
Preferred Qualifications
Depends on project
Details:
Preferred Student Year
First-year, Second-Year, Junior, Senior
Academic Term
Fall, Spring, Summer
I prefer to have students start during the above term(s).Volunteer
Yes
Yes indicates that faculty are open to volunteers.Paid
Yes
Yes indicates that faculty are open to paying students they engage in their research, regardless of their work-study eligibility.Work Study
Yes
Yes indicates that faculty are open to hiring work-study-eligible students.