Mentor Areas
The Kohli laboratory broadly focuses on DNA modifying enzymes and pathways, particularly those that contribute to genomic plasticity. The lab utilizes a broad array of approaches, including biochemical characterization of enzyme mechanisms, chemical synthesis of enzyme probes, and biological assays spanning immunology and virology to study the fundamental question of how a genomic diversity arises in nature. Mutation and modification of the genome play an important role in several physiologically relevant areas. Areas of interest include: 1. Decipher the molecular basis for deamination by AID/APOBEC enzymes and perturb deaminase immunological functions 2. Explore the interplay of cytosine modifying enzymes on DNA demethylation 3. Target pathogen pathways that promote evolution and resistance.
Description:
We aim to devise research projects for undergraduate that allow them to initially become familiar with the breadth of techniques used in the lab under supervision and to foster increasing independence over the time of their commitment.
Preferred Qualifications
Core Biochemistry, Chemistry and Biology.
Project Website
Learn more about the researcher and/or the project here. Kohli Lab
Details:
Preferred Student Year
First-year, Second-Year, Junior
Academic Term
Fall, Spring, Summer
I prefer to have students start during the above term(s).Volunteer
Yes
Yes indicates that faculty are open to volunteers.Paid
No
Yes indicates that faculty are open to paying students they engage in their research, regardless of their work-study eligibility.Work Study
Yes
Yes indicates that faculty are open to hiring work-study-eligible students.