Kelz, Max
Biomedical ScienceAnesthesia, Critical Care
Though millions of individuals are exposed to general anesthetics each year, the diverse molecular and neuronal mechanisms through which anesthetic drugs act to produce loss of consciousness are not fully understood.
The key topics that we are working on is eCPR, Lung Rescue, ECMO, and lung transplantation.
The Tsui lab works on real-time clinical AI and machine learning research and deployment for solving real-world problems using real-world data.
My lab is interested in studying the role of calcium dysregulation in pathology of Alzheimer's disease, major depression disorder and amyotrophic lateral sclerosis. We are repurposing intranasal dantrolene nanoparticles as new effective and disease-modifying drugs for these neurodegenerative diseases.
Research on brain circuit dysfunction that contributes to cognitive impairment associated with concussion.
We use mouse models to investigate neural circuits contributing to anesthetic hypnosis and recovery.
Our long term goal is to understand why some individuals are vulnerable or resilient to the potentially adverse effects of chronic stress.
Our research program is a true translational platform for bench to bedside to bench investigations in the field of resuscitation science.