Mentor Areas
Expertise in developing assays for metabolites involved in cellular oxidative stress and flux analysis of metabolites within intermediate metabolic pathways using stable-isotope dilution liquid chromatography mass spectrometry (LC-MS). Some of the routine assays include quantification of biomarkers of oxidative stress including isoprostanes, 8-oxo-dGuo and mechanisms of bioactive lipid formation and signaling pathways related to environmental exposures. As opposed to simply assessing exposure based on direct quantification of the exposure itself, this approach attempts to make use of downstream consequences of exposures.
Description:
The two major research interests of the Mesaros group include quantitatively understanding the pathological metabolic changes in Friedreich’s Ataxia (FRDA) and biomarkers of exposure and exposure-response to major pollutants.
Projects will vary. Interested students should contact us to discuss possibilities.
Preferred Qualifications
No technical skills required beside the strong desire to learn new skills.
Details:
Preferred Student Year
First-year, Second-Year, Junior, Senior
Academic Term
Fall, Spring, Summer
I prefer to have students start during the above term(s).Volunteer
Yes
Yes indicates that faculty are open to volunteers.Paid
Yes
Yes indicates that faculty are open to paying students they engage in their research, regardless of their work-study eligibility.Work Study
Yes
Yes indicates that faculty are open to hiring work-study-eligible students.