Mentor Areas
Developmental Biology, Model Organisms, Molecular Biology, Genomics, Genetics, Gene Expression, CRISPR and Gene Editing Technologies
Description:
As a single-celled zygote divides and differentiates, what factors are necessary to ‘tell’ each cell whether they are destined to become muscle, skin, or the myriad of other cell types in the body? Precise spatio-temporal coordination of basic processes such as transcription and DNA replication are essential to each individual cellular decision-making process. We leverage the exquisite invariant developmental lineage of the nematode Caenorhabditis elegans and the powerful tools and resources available in this model system to explore these questions. Work in the lab combines single-cell imaging and omics technologies with the generation of humanized worms to understand the control of embryonic fate decisions, and model defects in developmental disorders.
Preferred Qualifications
Basic molecular biology experience suggested, but not required.
Project Website
Learn more about the researcher and/or the project here. Sivaramakrishnan Lab Projects
Details:
Preferred Student Year
First-year, Second-Year, Junior, Senior
Academic Term
Fall, Spring, Summer
I prefer to have students start during the above term(s).Volunteer
Yes
Yes indicates that faculty are open to volunteers.Paid
Yes
Yes indicates that faculty are open to paying students they engage in their research, regardless of their work-study eligibility.Work Study
Yes
Yes indicates that faculty are open to hiring work-study-eligible students.