Sleep and brain development
We use the powerful model organism Drosophila to study the regulation and function of sleep during brain development.
Complex Brain Disorders
The lab aims to advance the understanding and treatment of complex brain disorders such as schizophrenia and related psychotic disorders.
Cancer Development
Investigating the mechanisms of breast cancer development and progression.
Exosome Therapy for Heart Failure
Utilize cell derived exosomes delivered via hydrogel into the heart muscle to enhance function and heart muscle growth.
Liver and kidney transplant research
Projects vary, but in general we use databases to understand opportunities to improve access to transplantation and study outcomes in various transplant populations.
Neuroblastoma developmental therapeutics
1. Familial Neuroblastoma.
2. ALK as a Tractable Molecular Target in Neuroblastoma.
3. Translational Research and Innovative Therapy Development.
4. Antibody Targeting of the Anaplastic Lymphoma Kinase Oncogene.
Development and application of artificial intelligence methods to biomedical data
Moore’s research focuses on the development and application of informatics methods for identifying complex relationship in biomedical data.
Neurobiology of Drug Addiction
Neurobiology of addiction: behavioral and cellular mechanisms.
ABCs in health and disease
Lessons in horror autotoxicus from age-associated B cells (ABCs).
Uncovering mechanisms of selective neuronal vulnerability in infantile neurodegenerative disorders
This project aims to analyze neuronal type specific protein synthesis landscape and how it evolves during development and differentiation to each neuronal population.