Hematopoietic Stem Cells and Leukemogenesis
Potential projects will involve using mouse and human experimental systems to study gene regulation and ribosome biogenesis in hematopoietic stem cells (HSCs), and the process by which abnormalities in these processes affects normal HSC function and produces leukemia.
Orthopaedic Joint Development and Tissue Engineering
We have several projects in cell lineage tracing, stem cell biology, mechanobiology, joint development, and tissue repair.
Injury and Chronic Pain: Biomechanics, Mechanisms & Treatments
Projects will vary. Interested students should contact us to discuss possibilities.
Neuroscience of traumatic brain injury
Research on brain circuit dysfunction that contributes to cognitive impairment associated with concussion.
Pediatric Airway Disorders and Bronchoscopy Innovation
Innovation in Pediatric Bronchoscopy and Airway Disorders
The biology of the endoplasmic reticulum in health and disease
Targeting the IRE-1/XBP-1 pathway for the treatment of B cell cancer.
Neuroendocrinology Of Energy Balance Control
Mesolimbic reward system and caudal brainstem; hormones involved in food intake and body weight regulations.
Leukodystrophy Center Of Excellence
Under Dr. Vanderver’s leadership, the multidisciplinary Leukodystrophy Center team is focused on creating new standards of care for children with leukodystrophies by advancing leukodystrophy gene discovery, creating new therapies, and supporting and advocating for patients and their families.
Understanding and controlling how cells work using synthetic biology
The Bugaj Lab studies how cells make decisions, and we build molecular tools to study and control cell function for basic and therapeutic application.