Sleep Disorders Research
In addition to our research studies in this topic area, students are also welcome to join our ongoing workshop related to learning clinical data management and statistics.
Arachidonic Acid Metabolites as Drug Target
I am interested in identifying novel factors related to the host-gut microbiota interactions that may influence the efficacy and/or toxicity of nonsteroidal anti-inflammatory drugs.
Development of next-generation chimeric antigen receptor immunotherapies for cancer
Dr. Ruella's laboratory focuses on the mechanisms of relapse after chimeric antigen receptor T cell (CART) immunotherapies with the goal of rationally design innovative combined immunotherapies for relapsing/refractory cancer.
Bioengineering and Biomaterials
Tissue-Engineering
Pediatric Airway Reconstruction
Controlled Drug Delivery
Developing quantitative molecular imaging methods for cancer research
Join force for developing molecular imaging markers from cells to animal models to human patients!
Cutaneous Lymphoma
Various Projects on Cutaneous T-cell Lymphoma, Cutaneous B-cell Lymphoma, Dermatopathology, Laser Capture Microdissection
Computational and Genomic Medicine
Integrating genomics, big data, and computing to drive medical innovations
Pregnancy and Pre-Term Birth Research
Dr. Simmons' main research interests are focused on the causal mechanistic links between the intrauterine milieu and type II diabetes and obesity in the adult with a focus on epigenetics and mitochondria function; the mechanisms underlying in utero exposures to environmental chemicals and the link to the later development of diabetes and obesity; the mechanisms underlying preterm birth.
Structural and functional understanding of TRP channels
The major goal of projects in the laboratory is to establish a detailed structural understanding of the mechanisms of TRP channels activation, desensitization and inhibition, which will help facilitate rational drug design for several human disease. We use cryo electron microscopy as a major tool to study TRP channels.