Pediatric oncology genomics and immunotherapy research
Dr. Bosse's laboratory focuses on the development of new immune-based therapies for this embryonal malignancy of the developing nervous system to both improve their understanding of the critical biologic mechanisms driving neuroblastoma tumorigenesis and to translate new transformative immunotherapeutics to the clinic.
Quantitative medical imaging and oxygen metabolism
Development and application of imaging biomarkers in the brain and other organs, including skeletal muscle and kidney.
Pediatric Anesthesiology Research
Exploring diverse research topics in pediatric anesthesiology, including pediatric difficult airway management, pediatric perioperative opioid use, EEG in infants under anesthesia, maternal-fetal anesthesia, neonatal perioperative outcomes, and others.
Carbon Dioxide Management
Achieving net-zero emissions by 2050: opportunities and challenges in state-specific pathways.
Functional Genomics and Single Cell Biology
1) Determine the neuronal activity induced epigenetic changes in adult mouse hippocampus
2) Using single cell sequencing approach to identify the molecular signatures during hippocampal development.
Investigating the Relationship Between Cushing’s Disease, Behavioral Changes and Cognitive Function
The purpose of this preliminary study is to evaluate the behavior and cognitive ability of dogs with Cushing’s as observed by their owners, and compare this to normal healthy dogs.
Magnetic Resonance Imaging Acquisition and Analysis
Dr. Tisdall's group develops new magnetic resonance imaging and analysis methods to expand the range of questions that MRI can answer.
Building a grassroots internet: Mesh networks in Philadelphia
This project brings together academics, community organizers and technologists to collaborate on a grassroots effort at increasing internet access in under-served communities in Philadelphia.
Human Cancer Immunotherapy Research
Our lab focuses on translational cancer immunology research, taking advantage of innovative clinical trials.